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Antibodies for human complement components: C1 inhibitor, C3, C4, C5b-9, Factor B, Factor I, Properdin.

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7985 Dunbrook Road, Suite A
San Diego, CA 92126

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Abi-1 Antibody

Rabbit Polyclonal Antibody

Cat. No.

251822

Unit

0.1 mg

Price $245.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Abelson interactor 1 (Abi-1) negatively regulates cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-1 plays a role in regulation of EGF-induced Erk pathway activation. Abi-1 is involved in cytoskeletal reorganization and EGFR signaling, and together with EPS8 participates in transduction of signals from Ras to Rac. A chromosomal aberration involving Abi-1 is a cause of acute leukemias.

Spec Container

Datasheet

Data Left

Isotype

Rabbit Ig

Applications

IHC

ICC

Species Reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Alternate Names

Abl interactor 1; Abelson interactor 1; Abi-1; Spectrin SH3 domain-binding protein 1; Eps8 SH3 domain-binding protein; Eps8-binding protein; e3B1; Nap1-binding protein; Nap1BP; Abl-binding protein 4; AblBP4; ABI1; SSH3BP1

Data Right

Accession No.

Q8IZP0

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Abi-1.

Application Notes

E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Images

Abi-1 staining in rat brain. Paraffin-embedded rat brain is stained with Abi-1 Antibody (Cat. No. 251822) used at 1:200 dilution.