Adrenomedullin Antibody

Catalog Number

250239

Unit

0.2 mg

Price

$750.00

Isotype

Applications

Species reactivity

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Description

Human adrenomedullin is a 52 amino-acid peptide (mw 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance. This antibody binds human adrenomedullin within aa 22-52 and shows no cross-reaction with CGRP.

Recommended Products

350034 Adrenomedullin [1-52] Peptide
350035 Adrenomedullin [22-52] Peptide

Alternate Names

Adrenomedullin; ADM; AM

Accession No.

P35318

Clonality

NA

Antigen

Synthetic human adrenomedullin 1-52

Application Notes

The ELISA dilution guideline applies to adrenomedullin coated directly at 1.0  ug/mL. The binding of Product Cat. No. 250239 to coated ADM is not inhibited by full-length adrenomedullin in solution up to a concentration of 1 µmol/L, but is inhibited by adrenomedullin (22-52) in solution.

E: 1:40,000

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.