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APC Antibody
Rat Monoclonal
Catalog Number250130 Unit0.1 mg Price$245.00 IsotypeRat IgG2aApplicationsE, WB, IFSpecies reactivityMFormatEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
DescriptionThe adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members. This antibody recognizes an epitope in the N-terminal half of the mouse APC in ELISA, Western blot and immunofluorescent staining. Recommended Products250131 APC Antibody Alternate NamesAdenomatous polyposis coli protein; protein APC; DP2.5; mAPC; Apc Accession No.ClonalityKT44 AntigenRecombinant mouse APC[788-1038] protein Application NotesE: 5 μg/ml WB: 1:2,000 IF: 1:200
StorageStore at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| Cytoskeleton Proteins, Signal Transduction, Cell Motility, Cancers | |
For research use only, not for diagnostic or therapeutic procedures.