BRCA1 Antibody

Rabbit Polyclonal Antibody

Cat. No.

200160

Unit

0.1 mg

Price $220.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Breast cancer type 1 susceptibility protein (BRCA1) plays a central role in DNA repair by facilitating cellular response to DNA repair. BRCA1 is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. BRCA1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BRCA1 are a cause of genetic susceptibility to breast and ovarian cancers.

Spec Container

Datasheet

Data Left

Isotype

Rabbit Ig

Applications

Species Reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 12.5% glycerol with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Alternate Names

Breast cancer type 1 susceptibility protein; RING finger protein 53; BRCA1; RNF53

Data Right

Accession No.

P38398

Clonality

ABT-1061

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BRCA1.

Application Notes

E: 1:500-1:1,000; WB: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Images

The BRCA1 Antibody is used in Western blot to detect BRCA1 in MDA-MB-435 cell lysate.

The BRCA1 Antibody (Cat. No. 200160) is used in Western blot to detect BRCA1 in rat ovary tissue lysate (data kindly provided by Dr. Anand Krishnan, University of Calgary).

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Antibody Products
Product Name	Applications	SKU	Price
BAP1 Antibody	E, WB, ICC	251709	$245.00
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BRCC45 Antibody	E, WB, IHC	253770	$310.00
COBRA1 Antibody	E, WB	253121	$330.00

Peptide Products
Product Name	Applications	SKU	Price
BRCA1 Peptide		350522	$50.00

For research use only, not for diagnostic or therapeutic procedures.

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