CD10 (HI10a) Antibody

Catalog Number

251055

Unit

2 ml

Price

$275.00

Isotype

Applications

Species reactivity

Format

Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

The CD10 (HI10a) antibody recognizes neutral endopeptidase, a 100-kDa type-II transmembrane glycoprotein, which is referred as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 antigen is expressed on a wide variety of normal and neoplastic cells including some subset of B and T lymphoid progenitors, germinal center cells, some granulocytes and fibroblasts. CD10 is a marker of common (pre-B) acute lymphocytic leukemias in which CD19, HLA-II and CD9 antigens are coexpressed. CD10 is a regulator of B cell growth and proliferation by hydrolysis of peptides having either proliferative or anti-proliferative functions.

Product Citations

Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York

Recommended Products

250943 CD10 (HI10a) Antibody
250999 CD10 (HI10a) Antibody, FITC

Alternate Names

Neprilysin; Neutral endopeptidase; NEP; Enkephalinase; Neutral endopeptidase 24.11; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; CD10 antigen; MME; EPN

Accession No.

P08473
NP_009218

Clonality

HI10a

Application Notes

FACS with whole blood: 100 μl blood + 20 μl antibody; FACS with cells: 10E6 cells + 20 μl antibody.

FACS: 1:200-1:1,000

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.