GLP-1 (8G9) Antibody

Mouse Monoclonal, Biotin-conjugated

Catalog Number

251104

Unit

0.05 mg

Price

$598.00

Isotype

Mouse IgG1

Applications

E

Species reactivity

Mk, H, M, R, Other

Format

Each vial contains 0.05 mg IgG in 0.05 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Description

Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody is specific for the amidated C terminus of the peptide and does not react with GLP-1 (7-37). 


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Alternate Names

Glucagon-like peptide 1; GLP-1; Glucagon; GCG

Accession No.

P01275

Clonality

8G9

Antigen

Synthetic GLP-1(7-36)amide coupled to carrier and adsorbed onto aluminum hydroxide gel.

Application Notes

Product Cat. No. 251104 is a biotin conjugate of Cat. No. 250364, which reacts with the amidated C-terminus of GLP-1 (7-36)amide, GLP-1 (9-36)amide and GLP-1 (1-36)amide. Product Cat. No. 250364 can be used as capture antibody in sandwich ELISA with Product Cat. No. 250366 or Product Cat. No. 250244 as detection antibody. Product Cat. No. 250364 has been used for the immunoblockade of endogenous GLP-1 in rats.

E: 1:8,000

 

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.

HormonesEndocrine System

For research use only, not for diagnostic or therapeutic procedures.