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Insulin Receptor Antibody

Rabbit Polyclonal Antibody
Cat. No. 
250721
Unit 
0.1 mg
Price $277.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance. This antibody is against the alpha subunit.