Ph. 858 586 0500    Toll Free 800 854 7453

P-glycoprotein Antibody

Rabbit Polyclonal Antibody
Cat. No. 
250820
Unit 
0.1 mg
Price $307.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

P-glycoprotein 1 (multidrug resistance protein 1, MDR1) is an energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Genetic variation in MDR1 are the cause for patients who do not respond to drug treatment. In mouse, the MDR gene family includes three or more related but distinct cellular genes. MDR1A is also called P-glycoprotein 3.