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SPAG5 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
250866
Unit 
0.1 mg
Price $314.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Sperm-associated antigen 5 (SPAG5) is necessary for normal spindle formation during mitosis. SPAG5 consists of a homodimer with a globular head domain and a long stalk or oligomer resulting in aster-like structures that bind to microtubules in the mitotic spindle. SPAG5 is highly expressed in testis and also detected at low levels in placenta, liver, pancreas, thymus and colon. SPAG5 expression is cell cycle-regulated, with an increase from prophase to cytokinesis and return to basal levels at the next G1 phase.