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Synapsin I (Ser603) Antibody

Rabbit Polyclonal Antibody
Phosphospecific Antibody
Cat. No. 
252583
Unit 
0.1 ml
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Otwo Biotech (Shenzhen) Inc.

Ste 518, 5th Bldg, Chuangye Rd
Zhongxing Industrial Park, Nanshan District
Shenzhen 518054

Phone: 0755-26055215
Fax: 0755-86372180
Email: sales@otwobiotech.com
Description 
Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 603 is the site on synapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases. Phosphorylation of this site is thought to regulate synaptic vesicle function.