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Tryptophan Hydroxylase (Ser260) Antibody

Rabbit Polyclonal Antibody

Phosphospecific Antibody

Cat. No.

252590

Unit

0.1 ml

Price $385.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Tryptophan 5-hydroxylase 1 (TPH) catalyzes the following reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin. TPH belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II). CaM K II phosphorylates Ser260 which lies within the regulatory domain of TPH.

Spec Container

Datasheet

Data Left

Isotype

Rabbit Ig

Applications

Species Reactivity

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

Alternate Names

Tryptophan 5-hydroxylase 1; tryptophan 5-momooxygenase 1; TPH1; TPH, TPRH; TRPH

Data Right

Accession No.

P09810

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser260 of rat tryptophan hydroxylase.

Application Notes

E: 1:1,000; WB: 1:1,000

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

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For research use only, not for diagnostic or therapeutic procedures.

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