Ph. 858 586 0500    Toll Free 800 854 7453

Alpha-MSH Peptide

Synthetic Peptide
Cat. No. 
350043
Unit 
5 mg
Price $195.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

MSH (melanocyte-stimulating hormone), produced by the pituitary gland, regulates the pigmentation of the skin by increasing melanin production in melanocytes. Alpha-MSH corresponds to aa 138-150 of corticotropin precursor (pro-opiomelanocortin, POMC). Alpha-MSH is an endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Alpha-MSH is an anti-inflammatory peptide which antagonizes proinflammatory mediators, including TNF-alpha, IL-6 and NO, and induces anti-inflammatory cytokine IL-10. It also inhibits food intake and induces penole erections following i.c.v. administration.