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Beta Amyloid [25-35] Peptide

Synthetic Peptide
Cat. No. 
350079
Unit 
2 mg
Price $85.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1), which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This peptide corresponds to the human beta-amyloid 25-35 peptide, which induces apoptosis in cells.