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Glucagon [19-29] Peptide

Synthetic Peptide
Cat. No. 
350201
Unit 
2 mg
Price $92.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Glucagon [19-29] corresponds to the C-terminal fragment of glucagon, a hormone secreted in the A cells of the islets of Langherans that plays a key role in glucose metabolism and homeostasis. Glucagon [19-29] is a potent Ca2+/Mg2+-ATPase inhibitor. It inhibits secretagogue-induced insulin secretion in beta-cells (IC50<1 pM) and Ca2+/Mg2+-ATPase activity in liver plasma membranes (IC50=0.75 nM). It also contributes to the positive inotropic effect of glucagon in cardiac cells by amplifying the cytosolic Ca2+ signal.