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GPS1573 Peptide

Synthetic Peptide

Cat. No.

350595

Unit

1 mg

Price $195.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

GPS1573 is a newly described potent and dose-dependent peptide antagonist of ACTH-stimulated melanocortin type 2 receptor (MC2R) activity in vitro (IC50 = 66 nM). GPS1573 antagonizes MC4R with IC50 of 950 nM, therefore showing selectivity for MC2R. The binding of ACTH to MC2R regulates steroidogenesis leading to metabolic diseases such as Cushing's disease in patients with pituitary dysfunctions.

Spec Container

Datasheet

Format

Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

Alternate Names

GPS1573; MC2R antagonist; Adrenocorticotropic hormone receptor antagonist

Accession No.

Q01718

1807.0 g/mol

Sequence

H-Nle-Pro-(D-Phe)-Arg-(D-Trp)-Phe-Lys-Ala-Val-Gly-Lys-Lys-Arg-Arg-NH2 or H-Nle-PfRwFKAVGKKRR-NH2

Composition

C86H139N27O16

Purity

Purity > 95% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.

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Product Name	Applications	SKU	Price
GPS1573 Peptide		350595	$215.00

For research use only, not for diagnostic or therapeutic procedures.

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GPS1573 Peptide

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