Ph. 858 586 0500    Toll Free 800 854 7453

RGDS Peptide

Synthetic Peptide
Cat. No. 
350365
Unit 
10 mg
Price $54.00

Order

Order directly from

Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD peptide acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts to fibronectin. The free RGDS peptide inhibits attachment of cells to fibronectin-coated substrates. The RGDS sequence is also a target for infectious agents (Treponema's syphilis, Mycobacterium's tuberculosis). RGDS can also block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes.