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CAM Ligands

Collagen II Antibody

$231.00
SKU: 250484

Type II collagen (COL2A1) is specific for cartilaginous tissues. Type II collagen is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Defects in COL2A1 are the cause of a variety of chondrodysplasia including hypochondrogenesis and osteoarthritis.

List price: $0.00
Price: $231.00

CD4 Antibody

$231.00
SKU: 250592

CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a lower level on monocytes. CD4 is involved in recognition of antigen presented along with MHC class II by APCs. CD4 is the primary cellular receptor for the human immunodeficiency virus (HIV).

List price: $0.00
Price: $231.00

CD4 (Mouse) Antibody

$430.00
SKU: 252512
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a lower level on monocytes. CD4 is involved in recognition of antigen presented along with MHC class II by APCs. CD4 is the primary cellular receptor for the human immunodeficiency virus (HIV).
List price: $0.00
Price: $430.00

Collagen IV (Mouse) Antibody

$231.00
SKU: 250485
Type IV collagen is the major structural component of glomerular basement membranes forming a "chicken-wire" meshwork together with laminins, proteoglycans and entactin/nidogen. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. Defects in type IV collagen are a cause of Alport syndrome autosomal recessive (APSAR), characterized by glomerulonephritis, renal failure, sensorineural deafness and eye abnormalities.
List price: $0.00
Price: $231.00

RGES Peptide

$44.00
SKU: 350367

The RGES peptide is a RGD-related peptide.

List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $44.00
Protein Family 
Pathway and Disease 
Cell Growth and Death
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Product Citations 
[1] Brzoska T et al. 2013. Journal. PLoS ONE. 8(2): e55466. PMID# 2338331
Alternate Names 
Fibronectin; Arg-Gly-Asp
Composition 
C16H29N7O8
Sequence 
H-Arg-Gly-Glu-Ser-OH or H-RGES-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
447.45 g/mol
Unit 
1 mg

E-cadherin Peptide

$50.00
SKU: 350496
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cancers
Cell Communication
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Epithelial cadherin; Uvomorulin; Cadherin-1; CAM 120/80; CD324 antigen; CDH1; CDHE; UVO
Composition 
C89H125N25O34S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200134 is selected from a sequence within the C-term region of human E-cadherin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2121.1 g/mol
Unit 
0.1 mg

RGDS Peptide

$54.00
SKU: 350365

The RGD peptide is the binding motif of fibronectin to cell adhesion molecules.

List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $54.00
Protein Family 
Pathway and Disease 
Cell Growth and Death
Format 
Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Product Citations 
[1] Brzoska T et al. 2013. Journal. PLoS ONE. 8(2): e55466. PMID# 2338331. [2] Kaminsky PM et al. 2012. Molecular Therapy. 20(5): 972-983. PMID#: 22233580
Alternate Names 
Fibronectin; Arg-Gly-Asp
Composition 
C15H27N7O8
Sequence 
H-Arg-Gly-Asp-Ser-OH or H-RGDS-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
433.4 g/mol
Unit 
10 mg

FGFR4 Peptide

$50.00
SKU: 350469
FGFR4 is a receptor for acidic fibroblast growth factor but does not bind to basic fibroblast growth factor.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cell Motility
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Fibroblast growth factor receptor 4; FGFR-4; CD334 antigen; FGFR4; JTK2; TKF
Composition 
C77H117N29O23S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200107 is selected from a sequence within the N-term region of human FGFR4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1849 g/mol
Unit 
0.1 mg

Fibrinolysis Inhibiting Factor Peptide

$54.00
SKU: 350174
Fibrinolysis inhibiting factor corresponds to the N-terminal end of alpha chain of fibrin increasing fibrinogen resistance to plasmin.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $54.00
Pathway and Disease 
Immune System
Format 
Each vial contains 2 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Fibrinogen alpah chain; fibrinopeptide A; FGA
Composition 
C18H31N7O5
Sequence 
H-Gly-Pro-Arg-Pro-OH or H-GPRP-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
425.5 g/mol
Unit 
2 mg

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