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Cellular Antigens

CD61 Peptide

$80.00
SKU: 350573
CD61, also called integrin beta-3, belongs to the integrin protein family that participates in cell adhesion and cell-surface mediated signalling by forming heterodimers of alpha and beta integrin chains. Integrin alpha-V/beta-3 is a receptor for cytoactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. These two integrins recognize the sequence RGD in a wide array of ligands. Integrin IIb/IIIa recognizes the sequence HHLGGGAKQAGDV in fibrinogen gamma chain. Following activation, integrin alpha-IIb/beta-3 supports platelet/platelet interaction through binding of soluble fibrinogen, leading to rapid platelet aggregation which physically plugs ruptured endothelial surface. Defects in CD61 are a cause of Glanzmann thrombasthenia, a blot clot disorder.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Pathway and Disease 
Cancers
Cell Communication
Cell Motility
Immune System
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD61; ITGB3; GP3A
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 250732 is selected from a sequence within the C-term region of human CD61. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Unit 
0.1 mg

Leptin Receptor (long) Peptide

$80.00
SKU: 350571
The Leptin receptor (OB receptor, OBR) is the receptor for the obesity factor (leptin). The Leptin Receptor is involved in the regulation of fat metabolism and in lymphopoiesis. The Leptin receptor is closely related to the gp130 signal transducing component common to the IL-6, LIF, CNTF and G-CSF receptors. The Leptin receptor has multiple isoforms (A-E) with isoform B (OBRb) being the long single-pass type I membrane receptor, isoform C (OBRa) carrying a short cytoplasmic domain, and isoform E a shorter secreted form. This blocking peptide is from the long form (isoform B).
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Pathway and Disease 
Signal Transduction; Signaling Molecules and Interaction; Endocrine System
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Leptin receptor; LEP-R; OB receptor; OB-R; HuB219; CD295 antigen; LEPR; DB; OBR
Composition 
C93H138N22O36
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 250738 is selected from a sequence within the N-term region of human Leptin Receptor (isoform B). For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
2140.2 g/mol
Unit 
0.1 mg

Fibronectin CS-1 Peptide

$84.00
SKU: 350176
The fibronectin CS-1 peptide corresponds to the cell attachment domain in the type-III homology connecting strand of fibronectin.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $84.00
Pathway and Disease 
Signaling molecules and interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Fibronectin; FN; Fibronectin type-III; CS1 peptide; CS-1 peptide
Composition 
C38H64N8O15
Sequence 
H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH or H-EILDVPST-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
872.97 g/mol
Unit 
2 mg

TLR4 Peptide

$80.00
SKU: 300110
Toll-like receptor family (TLR) has a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMP) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Toll-like receptor 4 (TLR4) cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6 to lead to NFkB activation, cytokine secretion and inflammatory response. TLR4 is highly expressed in placenta, spleen and peripheral blood leukocytes. Genetic variation in TLR4 is associated with age-related macular degeneration 10 (ARMD10), an irreversible vision loss.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Pathway and Disease 
Immune System
Infectious Diseases
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Toll-like receptor 4; hToll; CD284; TLR4
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 251111 is selected from a sequence within the N-term region of human TLR4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Unit 
0.1 mg

WKYMVM-NH2 Peptide

$86.00
SKU: 350428
This peptide is found to stimulate formation of InoPs through Phospholipase C. It may also have antimicrobial actions by activating Neutrophiles
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $86.00
Pathway and Disease 
Signaling Molecules and Interaction
Infectious Diseases
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
NONE
Composition 
C41H61N9O7S2
Sequence 
H-Trp-Lys-Tyr-Met-Val-Met-NH2 or H-WKYMVM-NH2
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
856.13 g/mol
Unit 
1 mg

L-Selectin Peptide

$88.00
SKU: 350251
Cell surface adhesion molecule. Mediates the adhesion of the Lymphosytes to endothelial cells in peripheral Lymph nodes.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $88.00
Pathway and Disease 
Signaling molecules and interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
L-selectin; Lymph node homing receptor; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; TQ1; gp90-MEL; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; CD62L antigen; SELL; LNHR; LYAM1
Composition 
C62H105N16O18S2
Sequence 
Human: H-Cys-Gln-Lys-Leu-Asp-Lys-Ser-Phe-Ser-Met-Ile-Lys-OH or H-CQKLDKSFSMIK-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
1426.75 g/mol
Unit 
1 mg

Apelin-13 Peptide

$90.00
SKU: 350066
Apelin is an endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $90.00
Pathway and Disease 
Immune System
Infectious Diseases
Signaling Molecules and Interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Apelin; APJ endogenous ligand; Apelin-13; APLN; APEL
Composition 
C69H111N23O16S
Sequence 
Human: H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH or H-QRPRLSHKGPMPF-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
1550.86 g/mol
Unit 
1 mg

MOG [35-55] Peptide (Rat)

$125.00
SKU: 350275
Myelin-oligodendrocyte glycoprotein (MOG) is a minor component of the myelin sheath. MOG is also a CNS-specific autoantigen for primary demyelination in multiple sclerosis. The developmentally late expression of MOG correlates with the later stages of myelogenesis, suggesting that MOG has a role in the completion, compaction and maintenance of myelin. MOG has many isoforms that can form homo- and heterodimers. It has been shown that the MOG [35-55] peptide induced anti-MOG(35-55) autoantibody production in C57BL/6 mice with 100% incident (10/10), providing quantitative support for the suitability of the MOG peptide for in vivo anti-MOG(35-55) autoantibody study.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $125.00
Pathway and Disease 
Cell Communication
Nervous and Sensory Systems
Neurodegenerative Disorders
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Myelin-oligodendrocyte glycoprotein; Mog
Composition 
C118H177N35O29S1
Sequence 
Rat: H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH or H-MEVGWYRSPFSRVVHLYRNGK-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
2582 g/mol
Unit 
1 mg

RC-160 Peptide

$150.00
SKU: 350357
RC-160 is the receptor for TNFSF8/CD30L. It may play a role in the refulation of cellular growth and transformation of activeated lymphoblasts.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $150.00
Pathway and Disease 
Signaling Molecules and Interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Tumor necrosis factor receptor superfamilyn member 8; CD30L receptor; Lymphocyte activation antigen CD30; Tnfrsf8; Cd30
Composition 
C57H68N12O9S2
Sequence 
Rat: H-D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (Cys2-Cys7) or H-fCYwKVCW- NH2 (Cys2-Cys7)
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
1129.4 g/mol
Unit 
1 mg

Fibrinogen-binding Peptide

$138.00
SKU: 350173
The fibrinogen-binding peptide inhibits platelet agregation and adhesion to fibrinogen and vitronectin by competing with the GPIIb/IIIa receptor.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $138.00
Pathway and Disease 
Cancers
Cell Communication
Cell Motility
Immune System
Signaling Molecules and Interaction
Format 
Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
GPIIb; GPIIIa; integrin alpha 2b; integrin beta 3
Composition 
C25H39N7O8
Sequence 
H-Glu-His-Ile-Pro-Ala-OH or H-EHIPA-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
565.63 g/mol
Unit 
10 mg

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