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Enzymes

ATM Peptide

$50.00
SKU: 350520
Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Protein Kinases
Pathway and Disease 
Cancers
Cell Growth and Death
Replication and Repair
Signal Transduction
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM
Composition 
C79H131N23O31S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200158 is selected from a sequence within the center region of human ATM. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1931.1 g/mol
Unit 
0.1 mg
Accession No.  
Q13315

MUTYH Peptide

$50.00
SKU: 350519
MUTYH is involved in oxydative DNA damage repair by initiating repair of A-oxoG to C-G by removing the inappropriately paired adenine base from the DNA backbone. Defects in MUTYH are the cause of colorectal and gastric cancers.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Replication and Repair
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
A/G-specific adenine DNA glycolase; MutY homolog; hMYH; MUTYH; MYH
Composition 
C71H126N26O22S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200157 is selected from a sequence within the C-term region of human MUTYH. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1760 g/mol
Unit 
0.1 mg
Accession No.  
Q9UIF7

Folliculin Peptide

$50.00
SKU: 350516
Folliculin (FLCN) plays a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculoma). Defects in FLCN are the cause of Birt-Hogg-Dube syndrome (fibrofolliculoma) and primary spontaneous pneumothorax (lung collapse).
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Folliculin; Birt-Hogg-Dube syndrome protein; BHD skin lesion fibrofolliculoma protein; FLCN; BHD
Composition 
C57H99N21O24S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200154 is selected from a sequence within the C-term region of human folliculin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1494.6 g/mol
Unit 
0.1 mg
Accession No.  
Q8NFG4

BMPR1A Peptide

$50.00
SKU: 350513
Upon ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane Ser/Thr kinases. The type I receptors are activated by the type II receptors by using a phosphorylation mechanism, and subsequently bind SMAD transcriptional regulators. Defects in BMPR1A are the cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2, which lead to gastrointestinal, breast, thyroid, endometrial and colon cancers.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Cellular Antigens
Enzymes
Protein Kinases
Receptors and Channels
Pathway and Disease 
Cancers
Signal Transduction
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Bone morphogenetic protein receptor type IA; Serine/threonine-protein kinase receptor R5; SKR5; Activin receptor-like kinase 3; ALK-3; CD292 antigen; BMPR1A; ACVRLK3
Composition 
C77H126N22O34S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200151 is selected from a sequence within the N-term region of human BMPR1A. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1936 g/mol
Unit 
0.1 mg
Accession No.  
P36894

NF1 Peptide

$50.00
SKU: 350512
Neurofibromin (NF1) stimulates the GTPase activity of Ras. Defects in NF1 are the cause of different types neurofibromatosis, colorectal cancer, and juvenile myelomonocytic leukemia.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Neurofibromin; Neurofibromatosis-related protein NF-1; Neurofibromin truncated; NF1
Composition 
C79H133N25O29S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200150 is selected from a sequence within the center region of human NF1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1929.1 g/mol
Unit 
0.1 mg
Accession No.  
P21359

CDK4 Peptide

$50.00
SKU: 350510
CDK4, a CMGC Ser/Thr protein kinase, is involved in the control of the cell cycle by forming a stable complex with D-type G1 cyclins. Defects in CDK4 are the cause of melanoma.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Protein Kinases
Pathway and Disease 
Cancers
Cell Communication
Cell Growth and Death
Immune System
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Cell division protein kinase 4; Cyclin-dependent kinase 4; PSK-J3; CDK4
Composition 
C93H138N28O29S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200148 is selected from a sequence within the C-term region of human CDK4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2144.3 g/mol
Unit 
0.1 mg
Accession No.  
P11802

PTEN Peptide

$50.00
SKU: 350507
PTEN is a dual-specificity protein phosphatase, dephosphorylating tyrosine-, threonine- and serine-phosphorylated proteins. PTEN has also a lipid phosphatase activity that is critical for its tumor suppression function. PTEN antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. Defects in PTEN are the cause of numerous cancers such as in Cowden disease (breast, thyroid and skin cancer predisposition), Lhermitte-Duclos disease, and head and neck squamous cell carcinoma.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Carbohydrate Metabolism
Cell Communication
Cell Growth and Death
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Phosphatase and tensin homolog; Mutated in multiple advanced cancers 1; MMAC1, TEP1
Composition 
C94H151N31O31S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200145 is selected from a sequence within the N-term region of human PTEN. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2243.4 g/mol
Unit 
0.1 mg
Accession No.  
P60484

SDHB Peptide

$50.00
SKU: 350503
SDHB catalyzes the formation of fumarate from succinate. SDBH forms part of complex II containing four subunits: a flavoprotein, an iron-sulfur protein and a cytochrome b composed of two integral membrane proteins. Defects in SDBH are a cause of pheochromocytoma, an adrenal medulla cancer.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Carbohydrate Metabolism
Energy Metabolism
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Succinate dehydrogenase ubiquinone iron-sulfur subunit; Ip; Iron-sulfur subunit of complex II; SDHB; SDH; SDH1
Composition 
C88H141N25O29S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200141 is selected from a sequence within the N-term region of human SDHB. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2077.3 g/mol
Unit 
0.1 mg
Accession No.  
P21912

Fumarase Peptide

$50.00
SKU: 350502
Fumarate hydratase (FH) is an enzyme that catalyzes the formation of malate from fumarate. FH also acts as a tumor suppressor. Defects in FH arer the cause of multiple leiomyomatosis, a growth of benign tumors in muscle and uterus.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Carbohydrate Metabolism
Energy Metabolism
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Fumarate hydratase; FH
Composition 
C95H145N23O28S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200140 is selected from a sequence within the C-term region of human fumarase. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2121.4 g/mol
Unit 
0.1 mg
Accession No.  
P07954

Exostosin-1 Peptide

$50.00
SKU: 350499
Exostosin-1 (EXT1) is a glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. EXT1 is a tumor suppressor. Defects in EXT1 are the cause of multiple exostoses disorders, i.e. skeletal deformities and bone tumors.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Pathway and Disease 
Cancers
Glycan Biosynthesis and Metabolism
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Putative tumor suppressor protein EXT1; Multiple exostoses protein 1; EXT1
Composition 
C92H160N30O27S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200137 is selected from a sequence within the C-term region of human Exostosin-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2150.5 g/mol
Unit 
0.1 mg
Accession No.  
Q16394

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