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Protein Kinases

INSR Peptide

$50.00
SKU: 350472
INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cell Communication
Endocrine System
Metabolic Disorders
Neurodegenerative Disorders
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Insulin receptor; CD220 antigen; IR; INSR
Composition 
C87H138N24O25S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200110 is selected from a sequence within the N-term region of human INSR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1952.2 g/mol
Unit 
0.1 mg

IGF1R Peptide

$50.00
SKU: 350471
IGF1R binds insulin-like growth factor 1 (IGF1) with high affinity and IGF2 with low affinity. The receptor has a tyrosine protein kinase activity necessary for the activation of the IGF1-stimulated downstream signaling cascade.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cancers
Cell Communication
Nervous and Sensory Systems
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Insulin-like growth factor I receptor; CD221 antigen; IGF-I receptor; IGF1R
Composition 
C72H125N25O24S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200109 is selected from a sequence within the C-term region of human IGF1R. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1757 g/mol
Unit 
0.1 mg

FGFR4 Peptide

$50.00
SKU: 350469
FGFR4 is a receptor for acidic fibroblast growth factor but does not bind to basic fibroblast growth factor.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cell Motility
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Fibroblast growth factor receptor 4; FGFR-4; CD334 antigen; FGFR4; JTK2; TKF
Composition 
C77H117N29O23S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200107 is selected from a sequence within the N-term region of human FGFR4. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1849 g/mol
Unit 
0.1 mg

FGFR2 Peptide

$50.00
SKU: 350468
FGFR2 is a receptor for acidic and basic fibroblast growth factors. Defects in FGFR2 are the cause of numerous craniofacial abnormalities such as Crouzon, Jackson-Weiss, and Apert syndromes.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cancers
Cell Motility
Signal Transduction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Fibroblast growth factor receptor 2; FGFR-2; Keratinocyte growth factor receptor 2; CD332 antigen; FGFR2; BEK; KGFR; KSAM
Composition 
C84H131N19O32S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200106 is selected from a sequence within the N-term region of human FGFR2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1951.1 g/mol
Unit 
0.1 mg

EphB2 Peptide

$50.00
SKU: 350467
EphB2 is a receptor for members of the ephrin-B family and acts as a tumor suppressor. Defects in EphB2 are involved in the development of prostate cancer metastasis to the brain.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cancers
Development and Behavior
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Ephrin type-B receptor 2 precursor; Tyrosine-protein kinase receptor EPH-3; DRT; Receptor protein-tyrosine kinase HEK5; ERK; Renal carcinoma antigen NY-REN-47; Tyrosine-protein kinase TYRO5; EPHB2; EPHT3; EPTH3
Composition 
C83H116N20O28S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200105 is selected from a sequence within the N-term region of human EphB2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1906 g/mol
Unit 
0.1 mg

EphA2 Peptide

$50.00
SKU: 350466
EphA2 is a receptor for members of the ephrin-A family. EphA2 binds to ephrin-A1, A3, A4 and A5.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Pathway and Disease 
Cancers
Signaling Molecules and Interaction
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Ephrin type-A receptor 2 precursor; Tyrosine-protein kinase receptor ECK; Epithelial cell kinase; EPHA2
Composition 
C85H143N27O21S1C85H143N27O21S1C85H143N27O21S1C85H143N27O21S1C85H143N27O21S1C85H143N27O21S1C85H143N27O21S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200104 is selected from a sequence within the C-term region of human EphA2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1911.3 g/mol
Unit 
0.1 mg

Phosphate Acceptor Peptide

$58.00
SKU: 350344
Receives the Phosphate from its donor peptide
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $58.00
Protein Family 
Pathway and Disease 
Cell Growth and Death
Transcription
Neurodegenerative Disorders
Cancers
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Histone H1.2; H1 VAR.1; H1c; Hist1hc; H1f2
Composition 
C41H74N16O11
Sequence 
Mouse: H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val-OH or H-RRKASGPPV-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
967.15 g/mol
Unit 
1 mg

Syntide 2 Peptide

$65.00
SKU: 350400
A synthetic peptide substrate for Protein Kinase II (CaMKII). It is derived from Glycogen synthase.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $65.00
Protein Family 
Pathway and Disease 
Signal Transduction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Glycogen [starch] synthase; muscle; EC 2.4.1.11; GYS1; GYS
Composition 
C68H122N20O18
Sequence 
Rabbit: H-Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH or H-PLARTLSVAGLPGKK-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
1507.85 g/mol
Unit 
1 mg

P1 Peptide

$78.00
SKU: 350315
P1 peptide participates in the signal transduction from the cell surface to the nucleus.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $78.00
Pathway and Disease 
Signal Transduction
Signaling molecules and interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Tyrosine-protein phosphatase non-receptor type 11; EC 3.1.3.48; Protein-tyrosine phosphatase 2C; PTP-2C; PTP-1D; SH-PTP3; SH-PTP2; SHP-2; Shp2; PTPN11; PTP2C; SHPTP2
Composition 
C39H63N11O13
Sequence 
Human: H-Gly-Ser-Phe-Leu-Val-Arg-Glu-Ser-OH or H-GSFLVRES-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
MW 
894 g/mol
Unit 
1 mg

S6 Kinase Substrate [229-239] Peptide

$68.00
SKU: 350039
Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents and mitogens and the dephosphorylation by growth arrest. The 229-239 peptide contain two phosphorylation sites, Ser235 and Ser236.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $68.00
Protein Family 
Pathway and Disease 
Endocrine System
Signal Transduction
Translation
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
40S ribosomal protein S6; phosphoprotein NP33; RPS6
Composition 
C54H104N24O14
Sequence 
Human: H-Ala-Lys-Arg-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-OH or H-AKRRRLSSLRA-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
MW 
1313.58 g/mol
Unit 
2 mg

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