Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents and mitogens and the dephosphorylation by growth arrest. The 229-239 peptide contain two phosphorylation sites, Ser235 and Ser236.
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Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
40S ribosomal protein S6; phosphoprotein NP33; RPS6
Human: H-Ala-Lys-Arg-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-OH or H-AKRRRLSSLRA-OH
Purity > 95% by HPLC
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Monday, December 17, 2012