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Transcription Factors

P1 Peptide

$78.00
SKU: 350315
P1 peptide participates in the signal transduction from the cell surface to the nucleus.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $78.00
Protein Family 
Transcription Factors
Protein Kinases
Pathway and Disease 
Signal Transduction
Signaling molecules and interaction
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Tyrosine-protein phosphatase non-receptor type 11; EC 3.1.3.48; Protein-tyrosine phosphatase 2C; PTP-2C; PTP-1D; SH-PTP3; SH-PTP2; SHP-2; Shp2; PTPN11; PTP2C; SHPTP2
Composition 
C39H63N11O13
Sequence 
Human: H-Gly-Ser-Phe-Leu-Val-Arg-Glu-Ser-OH or H-GSFLVRES-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
894 g/mol
Unit 
1 mg
Accession No.  
Q06124

FOSL1 Peptide

$80.00
SKU: 300112
Fos-related antigen 1 (FOSL1) is a protein that in humans is encoded by the FOSL1 gene. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $80.00
Protein Family 
Transcription Factors
Pathway and Disease 
Signal Transduction
Transcription
Format 
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
FOSL1; FOS-like antigen 1; Fos-related antigen 1; FRA-1; FRA1 
Composition 
C80H122N18O30
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 251523 is selected from a sequence within the center region of human FOSL1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1814.9 g/mol
Unit 
0.1 mg
Accession No.  
P15407

TAT Peptide

$100.00
SKU: 350402
Tat is the nuclear transcriptional activator of viral gene expression in HIV proliferation.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $100.00
Protein Family 
Transcription Factors
Receptors and Channels
Pathway and Disease 
Transcription
Signaling Molecules and Interactions
Infectious Diseases
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Tat protein
Composition 
C64H119N33O13
Sequence 
Human: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2 or H-YGRKKRRQRRR-NH2
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
1558.88 g/mol
Unit 
1 mg
Accession No.  
P04613

Antiestrogen Peptide

$122.00
SKU: 350064
Antiestrogen is a peptide competing with estrogens for binding to estrogen receptors. Antiestrogens are used in the treatment of breast cancers.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $122.00
Protein Family 
Receptors and Channels
Transcription Factors
Pathway and Disease 
Cancers
Endocrine System
Transcription
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Antiestrogen peptide; estrogen receptor antagonist; estradiol receptor antagonist
Composition 
C64H103N13O22S1P1
Sequence 
Human: H-Cys-Asn-Val-Val-Pro-Leu-Tyr(PO3H2)-Asp-Leu-Leu-Leu-Glu-OH or H-CNVVPLY(PO3H2)DLLLE-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
1469.65 g/mol
Unit 
1 mg
Accession No.  
P03372

TAT 2-4 Peptide

$134.00
SKU: 350403
Tat is the nuclear transcriptional activator of viral gene expression in HIV proliferation.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $134.00
Protein Family 
Transcription Factors
Receptors and Channels
Pathway and Disease 
Transcription
Signaling Molecules and Interactions
Infectious Diseases
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
Tat protein
Composition 
C132H240N66O29
Sequence 
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-OH or H-YGRKKRRQRRRGYGRKKRRQRRRG-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
3215.81 g/mol
Unit 
1 mg
Accession No.  
P04614

LZIC 293 Cell Lysate

$392.00
SKU: 405229
Antigen standard for leucine zipper and CTNNBIP1 domain containing (LZIC) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid (True ORF cDNA clone RC209433, OriGene Technologies, Inc.) and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
List price: $0.00
Image 
LZIC lysate validation: The LZIC 293 Cell Lysate (lane B) and Control Vector Cell Lysate (lane A) are used in Western blot to detect tagged-LZIC with a DDK Antibody.
Subcategory 
Cell Lysate
Price: $392.00
Protein Family 
Transcription Factors
Pathway and Disease 
Signaling Molecules and Interaction
ORF Clone URL 
http://www.origene.com/orf_clone/trueclone/NM_032368/RC209433/LZIC.aspx
Format 
This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Applications 
ELISA
WB
IP
Alternate Names 
leucine zipper and CTNNBIP1 domain-containing protein; leucine zipper and ICAT homologous domain-containing protein; protein LZIC; LZIC; MGC15436
Application Notes 
WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Storage 
Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Release Date 
Thursday, December 13, 2012
Unit 
0.1 mg
Accession No.  
NP_115744

IRF7 293 Cell Lysate

$672.00
SKU: 400595
Antigen standard for interferon regulatory factor 7 (IRF7), transcript variant a is a lysate prepared from HEK293T cells transiently transfected with aTrueORF gene-carrying pCMV plasmid (True ORF cDNA clone RC217934, OriGene Technologies, Inc.) and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
List price: $0.00
Image 
IRF7 lysate validation: The IRF7 293 Cell Lysate (lane B) and Control Vector Cell Lysate (lane A) are used in Western blot to detect tagged-IRF7 with a DDK Antibody.
Subcategory 
Cell Lysate
Price: $672.00
Protein Family 
Transcription Factors
Pathway and Disease 
Immune System
Infectious Diseases
ORF Clone URL 
http://www.origene.com/orf_clone/trueclone/accession/NM_001572/RC217934.aspx
Format 
This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Applications 
ELISA
WB
IP
Alternate Names 
isoform a is encoded by transcript variant a; interferon regulatory factor-7; IRF-7; IRF7; IRF-7H; IRF7A
Application Notes 
WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Storage 
Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Release Date 
Thursday, December 13, 2012
Unit 
0.1 mg
Accession No.  
NP_001563

FOXO3 293 Cell Lysate

$392.00
SKU: 400566
Antigen standard for forkhead box O3 (FOXO3), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid (True ORF cDNA clone RC209846, OriGene Technologies, Inc.) and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
List price: $0.00
Image 
FOXO3 lysate validation: The FOXO3 293 Cell Lysate (lane B) and Control Vector Cell Lysate (lane A) are used in Western blot to detect tagged-FOXO3 with a DDK Antibody.
Subcategory 
Cell Lysate
Price: $392.00
Protein Family 
Transcription Factors
Pathway and Disease 
Cancers
Cell Growth and Death
Immune System
Nervous and Sensory Systems
Transcription
ORF Clone URL 
http://www.origene.com/orf_clone/trueclone/accession/NM_001455/RC209846.aspx
Format 
This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Applications 
ELISA
WB
IP
Alternate Names 
forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; forkhead box O3A; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; FOXO3; AF6q21; DKFZp781A0677; FKHRL1; FKHRL1P2; FOXO2; FOXO3A; MGC12739; MGC31925
Application Notes 
WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Storage 
Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Release Date 
Thursday, December 13, 2012
Unit 
0.1 mg
Accession No.  
NP_001446

Human PPAR gamma

$235.00
SKU: 600283
Peroxisome Proliferator-Activated Receptor Gamma (PPAR-gamma) is a nuclear receptor that functions as a transcription factor and plays an important role in controling differentiation and fatty acid metabolism. Activation of PPAR-gamma is vital in modulating the expression of metabolic control proteins and consequently controling fatty acid metabolism in cardiac muscle. This marker is useful as a drug target for therapeutic intervention in cardiac disease.
List price: $0.00
Price: $235.00

Sox2 Antibody

$315.00
SKU: 254505
Transcription factor SOX-2 (Sox2) forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Defects in Sox2 are the cause of microphthalmia syndromic type 3 (MCOPS3). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities.
List price: $0.00
Price: $315.00

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