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Translation Factors

AEBP1 Peptide

$50.00
SKU: 350560
Adipocyte enhancer-binding protein 1 (AEBP1) up-regulates MAP-kinase activity leading to enhanced proliferation and reduced differentiation of the adipocyte. AEBP1 also up-regulates NF-kappa-B activity in macrophages via phosphorylation and subsequent degradation of I-kappa-B-alpha. This leads to enhanced macrophage inflammatory responsiveness. It can also act as a transcriptional repressor.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Translation Factors
Transcription Factors
Protein Kinases
Enzymes
Pathway and Disease 
Immune System
Signaling Molecules and Interaction
Transcription
and Translation.
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
AEBP1; ACLP; AE-binding protein 1; Aortic carboxypeptidase-like protein; Adipocyte enhancer-binding protein 1
Composition 
C93H136N18O36S1C93H136N18O36S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200198 is selected from a sequence within the N-term region of AEBP1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2114.2 g/mol
Unit 
0.1 mg
Accession No.  
Q14113

Slicer Peptide

$50.00
SKU: 350549
Eukaryotic translation initiation factor 2C 2, also known as Slicer protein or Argonaute-2, provides endonuclease activity to RNA-induced silencing complexes (RISC). Slicer cleaves siRNA/mRNA heteroduplexes bound to RISC. Slicer is essential for embryonic development and RNA-mediated gene silencing (RNAi). Slicer is localised in processing bodies (P bodies) that contain decapping enzymes, a 5'-to-3' exoribonuclease, LSm proteins, and RNAi machinery components.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Enzymes
Translation Factors
Pathway and Disease 
Development and Behavior
Translation
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Eukaryotic translation initiation factor 2C 2; elF2C 2; elF-2C 2; Argonaute-2; Slicer protein; PAZ Piwi domain protein; PPD; ElF2C2; AGO2
Composition 
C90H150N24O26S2
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200187 is selected from a sequence within the N-term region of human Slicer. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
2048.4 g/mol
Unit 
0.1 mg
Accession No.  
Q9UKV8

SC35 Peptide

$50.00
SKU: 350543
Splicing factor SC35 (SC35) is necessary for the splicing of pre-mRNA by forming the earliest ATP-dependent splicing complex and interacting with spliceosomal components bound to the 5'- and 3'-splice sites during spliceosome assembly. SC35 is used to detect nuclear speckles or interchromatin granule clusters.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Price: $50.00
Protein Family 
Translation Factors
Pathway and Disease 
Folding
Sorting and Degradation
Transcription
Translation
Format 
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
Alternate Names 
Splicing factor, arginine/serine-rich 2; Splicing factor SC35; SC35; Splicing component, 35 kDa; Protein PR264; SFRS2
Composition 
C76H127N23O30S1
Sequence 
The synthetic peptide used to raise the antibody Cat. No. 200181 is selected from a sequence within the C-term region of human SC35. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity 
Purity > 80% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
Blocking Peptide
MW 
1875 g/mol
Unit 
0.1 mg
Accession No.  
Q01130

S6-1 Peptide

$90.00
SKU: 350372
S6-1 Peptide is the major substrate of protein kinasses in eukaryote ribosomes. The phosphorylation is stimulated by growth factors , tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest.
List price: $0.00
Storage 
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Price: $90.00
Protein Family 
Ribosomes
Translation Factors
Pathway and Disease 
Signal Transduction
Translation
Endocrine System
Format 
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alternate Names 
40S ribosomal protein S6; Phosphoprotein NP33; RPS6; OK/SW-cl.2
Composition 
C39H75N17O11
Sequence 
Human: H-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-OH or H-RRLSSLRA-OH
Purity 
Purity > 95% by HPLC
Solubility 
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Release Date 
Monday, December 17, 2012
Subcategory 
Synthetic Peptide
MW 
958.14 g/mol
Unit 
2 mg
Accession No.  
P62753

ZBTB7A Antibody

$265.00
SKU: 254411

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR.

Western blot analysis of ZBTB7A in human ovary tissue lysate with ZBTB7A Antibody at (A) 1 and (B) 2 ug/ml.
ZBTB7A staining in ovary. Paraffin-embedded human ovary is stained with ZBTB7A Antibody (Cat. No. 254411) used at 1:100 dilution.
List price: $0.00
Price: $265.00

MPS1 (7E3) Antibody

$308.00
SKU: 252892
MPS1 (Metallopan-stimulin 1) is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. MSP1 has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus.
List price: $0.00
Price: $308.00

MPS1 (4A12) Antibody

$308.00
SKU: 252891
MPS1 (Metallopan-stimulin 1) is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. MSP1 has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus.
List price: $0.00
Price: $308.00

FMR1 (4G9) Antibody

$308.00
SKU: 252868
FMR1 (Fragile X mental retardation protein 1) is an RNA-binding protein. FMR1 associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).
List price: $0.00
Price: $308.00

LIN28 (6D1F) Antibody

$352.00
SKU: 252822
LIN28 (lin-28 homolog) was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.
List price: $0.00
Price: $352.00

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