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Rat GDNF

Recombinant Active Protein
Cat. No. 
600378
Unit 
0.01 mg
Price $250.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Glial Cell Line-Derived Neurotrophic Factor, or GDNF, is a neurotrophic factor that is closely related to other neurotrophic factors such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes receptors known as RET, and GFR alpha 1-4 to promote dopamine uptake, survival and differentiation of neurons. Rat GDNF is produced in E.coli. Recombinant rat GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.1 kDa.