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ADRB2 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
251604
Unit 
0.1 mg
Price $323.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

The beta-2 adrenergic receptor is a G-protein coupled adrenergic receptor with 30-fold higher affinity for epinephrine than norepinephrine. Agonist binding to the beta-2 adrenergic receptor initiates signal transduction pathways via activation of adenylyl cyclases. There are numerous physiological effects of beta-2 adrenergic receptor activation, including smooth muscle relaxation, blood vessel dilation, increased heart rate, and insulin secretion. The Gly-16 allele is overrepresented in individuals affected by nocturnal asthma as compared to controls, and appears to be an important genetic factor in the expression of this asthmatic phenotype.