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Histone H3A Antibody

Rabbit Polyclonal Antibody
Cat. No. 
250690
Unit 
0.1 mg
Price $323.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Histones are the core components of the nucleosomes that wrap and compact DNA into chromatin. DNA compacting limits accessibility to the cellular machineries which require DNA as template. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. The accessibility of DNA is regulated by post-translational modifications of histones such as acetylation, methylation and phosphorylation. The nucleosome is a histone octamer containing two molecules each of histone proteins H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.