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IFNAR1 (Ser535/539) Antibody

Phosphospecific Antibody
Rabbit Polyclonal Antibody
Cat. No. 
0.1 ml
Price $350.00


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Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
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Interferon-a Receptor, Type I, Subunit I (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. This interferon receptor is a receceptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Down regulation of IFNAR1 is influenced by phosphorylation of Serine 535 and 539.