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IL1 Receptor Antagonist Antibody

Mouse Monoclonal Antibody
Cat. No. 
250102
Unit 
0.1 mg
Price $299.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
The interleukin-1 receptor antagonist (IL-1ra) inhibits the activity of IL-1 by binding to the IL-1 receptor but has no IL-1 like activity. IL-1ra has 4 isoforms produced by alternative splicing, only isoform 1 is secreted. The intracellular forms of IL-1ra are predominantly expressed in epithelial cells. Under the name Kineret (Amgen), IL-1ra is used to treat patients with moderate to severe case of active rheumatoid arthritis by slowing the progression of the structural damages. This antibody recognizes human IL-1ra in ELISA.