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NMDAR2B (Ser1480) Antibody

Rabbit Polyclonal Antibody
Phosphospecific Antibody
Cat. No. 
252564
Unit 
0.1 ml
Price $385.00

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350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Glutamate [NMDA] receptor subunit epsilon-2 (N-methyl D-aspartate receptor subtype 2B receptor or NMDA NR2B) is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NMDA NR2B forms heteromeric channel of a zeta subunit, a epsilon subunit (GRIN2A , GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). NMDA NR2B is sprimarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells. Phosphorylation of Ser1480 decreases the surface expression of NMDA NR2B subunit.