Ph. 858 586 0500    Toll Free 800 854 7453

SPARC Antibody

Rabbit Polyclonal Antibody
Cat. No. 
0.1 mg
Price $323.00


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350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252

Secreted protein acidic and rich in cysteine (SPARC) regulates cell growth through interactions with the extracellular matrix and cytokines. SPARC binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. SPARC has two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity. SPARC is expressed at high levels in tissues undergoing morphogenesis, remodeling and wound repair.