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TIF1-beta Antibody

Rabbit Polyclonal Antibody
Cat. No. 
252106
Unit 
0.1 mg
Price $330.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Transcription intermediary factor 1-beta (TIF1-beta) forms a complex with a KRAB-domain transcription factor and increases the efficiency of KRAB-mediated repression. TIF1-beta silences transcription through an interaction with HP1 proteins. TIF1-beta acts as a corepressor of transcription for the KRAB zinc finger proteins and as a moderator of the repression activity. TIF1-beta plays a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of the Alpha-1-acid glycoprotein gene.