TRAF1 Antibody
Rabbit Polyclonal Antibody
Cat. No.
251580
Unit
0.1 mg
Price
$292.00
Order
Order directly from
Abbiotec
938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA
Phone: 1 858 586 0500 x100,
1 800 854 7453
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description
TNF receptor-associated factor 1 (TRAF1) is an adapter molecule that regulates the activation of NF-kappa-B and JNK. TRAF1 plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.