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ZNF346 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
254365
Unit 
0.1 mg
Price $292.00

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938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
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Description 
ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four C(2)H(2)-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.