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Fibrinogen Gamma Chain Dodecapeptide

Synthetic Peptide
Cat. No. 
350172
Unit 
1 mg
Price $73.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

The dodecapeptide corresponds to the C-term end of fibrinogen gamma chain responsible of platelet aggregation. The fibrinogen gamma-chain dodecapeptide inhibits agonist-induced platelet aggregation by competing with fibrinogen for binding to platelet integrin receptor GPIIb/IIIa (glycoprotein IIb-IIIa), also known as integrin alphaIIb-beta3. This peptide exhibits hemostatic, pro-thrombotic activity and enhancing thrombus formation. It is clinically used as a platelet substitute.