Ph. 858 586 0500    Toll Free 800 854 7453

Gamma-1 MSH Peptide

Synthetic Peptide
Cat. No. 
1 mg
Price $99.00


Order directly from


350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252

MSH (melanocyte-stimulating hormone), produced by the pituitary gland, regulates the pigmentation of the skin by increasing melanin production in melanocytes. Gamma-1 MSH corresponds to aa 77-87 of corticotropin precursor (pro-opiomelanocortin, POMC). Gamma-MSH peptides contain a core 7-amino-acid residue sequence similar to ACTH(4-10). Gamma-1 MSH is an endogenous melanocortin MC3 receptor agonist (pKi=7.46) that displays a 40-fold selectivity over MC4. It increases the release of extracellular dopamine, which induces grooming and vertical activity (rearing) in rats. It also exhibits hypertensive, tachycardic and short-term analgesic activity in vivo. Gamma-1 MSH facilitates learning and memory. It can also affect inflammatory, immune response and peripheral nerve regeneration.