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HER2/neu [654-662] Peptide

Synthetic Peptide
Cat. No. 
350219
Unit 
1 mg
Price $88.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

The HER2/neu oncogene encodes a 185-kDa transmembrane protein with homology to the epidermal growth factor receptor. HER2 is overexpressed in 30-40% of breast and ovarian cancers, and this overexpression was shown to correlate with aggressiveness of malignancy and poor prognosis. The HER2/neu [654-662] peptide, also called HER2/neu GP2, is a tumor-associated antigen shared among several adenocarcinomas including pancreatic carcinoma, suggesting a common mechanism of recognition of these human tumors by T lymphocytes.