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MBP [87-99] Peptide

Synthetic Peptide
Cat. No. 
350264
Unit 
1 mg
Price $76.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Myelin basic protein (MBP) is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. Numerous MBP isoforms are involved in myelin membrane formation and stabilization by interacting with the lipids in the myelin membrane. The major form of MBP is a protein of about 18.5 kDa (170 aa). MBP [87-99] Peptide is a major encephalitogenic epitope in MBP that induces T-cell proliferation with Th1 polarization in the CNS. This peptide is a major antigenic component implicated in the pathophysiology of multiple sclerosis.