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Human GST Omega-1 A140D

Recombinant Protein
Cat. No. 
600251
Unit 
0.01 mg
Price $250.00

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938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Glutathione S-Transferase Omega 1 (GSTO1) exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities: RX + glutathione = HX + R-S-glutathione. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-to-aspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation. GSTO1 140D comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 140D mutant mature protein and is expressed in E. coli with an amino-terminal hexahistidine tag.