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Human ILK-1

Recombinant Protein
Cat. No. 
600258
Unit 
0.01 mg
Price $250.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Integrin-linked kinase (ILK-1) acts as a mediator of inside-out integrin signaling. It is part of focal adhesion complex ILK-PINCH, considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Integrin-linked kinase is implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Integrin-linked kinase phosphorylates beta-1 and beta-3 integrin subunits on serine and threonine residues. Recombinant ILK-1 comprises a 452 amino acid fragment (1-452) corresponding to the mature ILK-1 full-length protein and is expressed in E. coli with an amino-terminal hexahistidine tag.