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Human VEGFR-1

Recombinant Protein
Cat. No. 
600311
Unit 
0.01 mg
Price $250.00

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938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Vascular Endothelial Growth Factor Receptor-1 (VEGFR-1) belongs to a family of five receptor tyrosine kinase receptors that are specific to a number of angiogenic factors including VEGF and PDGF, and are therefore thought to play a role in the angiogenic process. VEGFR-1 is expressed in two forms, predominantly on endothelial cells, giving rise to a full-length membrane bound receptor and a truncated soluble receptor. Elevated levels of the soluble form of this VEGF receptor are used in the diagnosis of pathological conditions. Recombinant VEGFR-1 comprises a 298 amino acid fragment (31-328) corresponding to the IgG-like domains 1-3 from the mature soluble VEGFR protein. VEGF-R1 is expressed in E. coli with an amino-terminal hexahistidine tag.