Rat GDNF
Recombinant Active Protein
Cat. No.
600378
Unit
0.01 mg
Price
$250.00
Order
Order directly from
Abbiotec
938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA
Phone: 1 858 586 0500 x100,
1 800 854 7453
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description
Glial Cell Line-Derived Neurotrophic Factor, or GDNF, is a neurotrophic factor that is closely related to other neurotrophic factors such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes receptors known as RET, and GFR alpha 1-4 to promote dopamine uptake, survival and differentiation of neurons. Rat GDNF is produced in E.coli. Recombinant rat GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.1 kDa.