Rat MIP-1 alpha

Recombinant Active Protein

Cat. No.

600380

Unit

0.02 mg

Price $250.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Macrophage Inflammatory Protein-1 alpha (MIP-1alpha), also known as CCL3, is produced by macrophages and is thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1alpha can exist as a naturally occurring heterodimer with MIP-1beta and has been shown to have antiviral activity against HSV-1. Rat MIP-1 alpha is produced in E.coli. Recombinant rat MIP-1 alpha is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.

Spec Container

Datasheet

Format

Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Alternate Names

C-C motif chemokine 3; small-inducible cytokine A3; macrophage inflammatory protein 1-alpha; MIP-1-alpha; tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; G0S19-1 protein; SIS- beta; PAT 464.1; MIP-1-alpha(4-69); LD78-alpha(4-69); CCL3; G0S19-1; MIP1A; SCYA3

Accession No.

P50229

7800 Da

Sequence

APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA

Source

E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Purity

Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Application Notes

The activity is determined by the ability to chemoattract human PBMCs at 1-10 ng/mL. Specific activity: 1 x 10e6 units/mg

Storage

Store at -20C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

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Rat MIP-1 alpha

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